Primaquine (diphosphate) (Standard)

Primaquine (diphosphate) (Standard)

• CAS Number: 63-45-6
• UNSPSC Description: Primaquine (diphosphate) (Standard) is the analytical standard of Primaquine (diphosphate). This product is intended for research and analytical applications. Primaquine diphosphate is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine diphosphate prevents relapse in vivax and ovale malaria[1].
• Target Antigen: Parasite
• Type: Reference Standards
• Related Pathways: Anti-infection
• Field of Research: Cancer; Infection
• Assay Protocol: https://www.medchemexpress.com/primaquine-diphosphate-standard.html
• Smiles: CC(NC1=C2N=CC=CC2=CC(OC)=C1)CCCN.O=P(O)(O)O.O=P(O)(O)O
• Molecular Weight: 455.34
• References & Citations: [1]Ashley EA, et al. Primaquine: the risks and the benefits. Malar J. 2014 Nov 3;13:418.|[2]Qigui Li, et al. Assessment of the prophylactic activity and pharmacokinetic profile of oral tafenoquine compared to primaquine for inhibition of liver stage malaria infections. Malar J. 2014 Apr 14:13:141. |[3]Ji-Hyang Kim, et al. Primaquine Inhibits the Endosomal Trafficking and Nuclear Localization of EGFR and Induces the Apoptosis of Breast Cancer Cells by Nuclear EGFR/Stat3-Mediated c-Myc Downregulation. Int J Mol Sci. 2021 Nov 30;22(23):12961.
• Shipping Conditions: Room temperature