HBV-IN-48

CAT: 0804-HY-168045Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-168045Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

HBV-IN-48 is an HBV inhibitor. HBV-IN-48 has antiviral activity against HBV in HepDE19 cells, with an EC50 value of 0.005 μM. HBV-IN-48 can reduce serum HBV DNA levels in mouse models of HBV infection[1].

CAS Number

2743466-04-6

UNSPSC

12352005

Target

DNA/RNA Synthesis; HBV

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hbv-in-48.html

Smiles

O=C(C(N1)=CC2=C1C=C(F)C(F)=C2)N([C@@H]3COCC4=C3C5=C(C(N4)=O)C=C(F)C(F)=C5)C

Molecular Formula

C22H15F4N3O3

Molecular Weight

445.37

References & Citations

[1]Mesaros E F, et al. Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators[J]. ACS Medicinal Chemistry Letters, 2024.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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