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GM130 rabbit pAb

CAT: 0855-ES16150-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES16150-01Size:50 µL
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Background
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs) . Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010]
Description
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010],
Product Name Alternative
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; Golgin-95)
UniProt
Q08379
Swiss Prot
Q08379
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human GM130
Target
GM130
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
112-130kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
112-130kD
Fragment
IgG
Subcellular Location
Golgi apparatus, cis-Golgi network membrane ; Peripheral membrane protein ; Cytoplasmic side . Endoplasmic reticulum-Golgi intermediate compartment membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton, spindle pole . Associates with the mitotic spindle during mitosis (PubMed:26165940) . .
Other Product Names
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; Golgin-95)
Gene ID (Human)
2801

UniProtKB · Q08379

Golgin subfamily A member 2

GOGA2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q08379
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GOLGA2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A0C4DGS5, Q6GRM9, Q9BRB0, Q9NYF9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionMitosisProtein transportTransport

Domain

Coiled coil

Cellular component

CytoplasmCytoskeletonGolgi apparatusMembraneMicrotubule

Disease

Disease variantIntellectual disability

PTM

MethylationPhosphoprotein

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