Autocamtide-2-related inhibitory peptide (TFA)

Autocamtide-2-related inhibitory peptide (TFA)

• UNSPSC Description: Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
• Target Antigen: Autophagy; CaMK
• Type: Peptides
• Related Pathways: Autophagy;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/Autocamtide-2-related_inhibitory_peptide_TFA.html
• Purity: 95.24
• Solubility: H2O : 110 mg/mL (ultrasonic)
• Smiles: O=C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N.OC(C(F)(F)F)=O
• Molecular Weight: 1611.76
• References & Citations: [1]Ishida A, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported