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Rasagiline (Standard)

CAT: 0804-HY-14605AR-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14605AR-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rasagiline (Standard) is the analytical standard of Rasagiline. This product is intended for research and analytical applications. Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively[1]. Rasagiline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
136236-51-6
Product Name Alternative
(R) -AGN1135 (Standard) ; TVP1012 (Standard)
UNSPSC
12352005
Target
Monoamine Oxidase; Reference Standards
Type
Reference Standards
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rasagiline-standard.html
Smiles
C#CCN[C@H]1C2=CC=CC=C2CC1
Molecular Formula
C12H13N
Molecular Weight
171.24
References & Citations
[1]M B Youdim, et al. Rasagiline [N-propargyl-1R (+) -aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol. 2001 Jan;132 (2) :500-6.|[2]Shawna Tazik, et al. Comparative neuroprotective effects of Rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis. Neurotox Res. 2009 Apr;15 (3) :284-90.|[3]Nadia Stefanova, et al. Rasagiline is neuroprotective in a transgenic model of multiple system atrophy. Exp Neurol. 2008 Apr;210 (2) :421-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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