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Hirsutanonol

CAT: 0804-HY-N4044-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N4044-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hirsutanonol ((5S) -Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 (COX-2) expression. Hirsutanonol has anti-filarial with an IC50 value of 44.11 μg/mL for microfilariae[1].
CAS Number
41137-86-4
Product Name Alternative
(5S) -Hirsutanonol
UNSPSC
12352005
Target
COX; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/hirsutanonol.html
Solubility
10 mM in DMSO
Smiles
OC1=C(O)C=CC(CCC(C[C@@H](O)CCC2=CC(O)=C(O)C=C2)=O)=C1
Molecular Formula
C19H22O6
Molecular Weight
346.37
References & Citations
[1]Lee MW, et al. Inhibition of cyclooxygenase-2 expression by diarylheptanoids from the bark of Alnus hirsuta var. sibirica. Biol Pharm Bull. 2000 Apr;23 (4) :517-8.|[2]Yadav D, et al. Antifilarial diarylheptanoids from Alnus nepalensis leaves growing in high altitude areas of Uttarakhand, India. Phytomedicine. 2013 Jan 15;20 (2) :124-32.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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GTR19181384Hirsutanonol
TN4211Hirsutanonol 5-O-glucoside

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