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(S) -Oxiracetam

CAT: 0804-HY-126049-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126049-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -oxiracetam (S-ORC) is an inhibitor targeting apoptosis. S-ORC reduces brain infarct size and lessens neurological dysfunction in middle cerebral artery occlusion/reperfusion (MCAO/R) models. S-ORC prevents neuronal apoptosis via activating PI3K/Akt/GSK3β signaling pathway via α7 nAChR after ischemic stroke. S-ORC can prevent neuronal death after ischemic stroke[1].
CAS Number
88929-35-5
Product Name Alternative
(S) - (-) -Oxiracetam; (S) -ISF2522
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-oxiracetam.html
Purity
99.56
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(CN1C(C[C@@H](C1)O)=O)N
Molecular Formula
C6H10N2O3
Molecular Weight
158.16
Precautions
H315, H319, H335
References & Citations
[1]Fan W, et al. S-oxiracetam ameliorates ischemic stroke induced neuronal apoptosis through up-regulating α7 nAChR and PI3K / Akt / GSK3β signal pathway in rats. Neurochem Int. 2018 May;115:50-60.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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