Cryptdin-4 (Mouse)

Cryptdin-4 (Mouse)_x000D_ Catalog number: MDP0853_x000D_ CAS Number: 100742-61-8_x000D_ Sequence: Gly-Leu-Leu-Cys-Tyr-Cys-Arg-Lys-Gly-His-Cys-Lys-Arg-Gly-Glu-Arg-Val-Arg-Gly-Thr-Cys-Gly-Ile-Arg-Phe-Leu-Tyr-Cys-Cys-Pro-Arg-Arg (Disulfide bonds between Cys4-Cys29, Cys6-Cys21, and Cys11-Cys28)_x000D_ Amount: 100 ug_x000D_ Molecular Weight: 3755.2 g/mol_x000D_ Supplied as: Powder_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ WARNING: For in vitro Research Use Only. NOT for use on humans or animals._x000D_ Grade: Biotechnology grade. All products are highly pure._x000D_ _x000D_ References:_x000D_ 1: Jing W, Hunter HN, Tanabe H, Ouellette AJ, Vogel HJ. Solution structure of cryptdin-4, a mouse paneth cell alpha-defensin Biochemistry. 2004 Dec 21;43(50):15759-66._x000D_ 2: Masuda K, Sakai N, Nakamura K, Yoshioka S, Ayabe T. Bactericidal activity of mouse α-defensin cryptdin-4 predominantly affects noncommensal bacteria J Innate Immun. 2011;3(3):315-26._x000D_ 3: Tanabe H, Qu X, Weeks CS, Cummings JE, Kolusheva S, Walsh KB, Jelinek R, Vanderlick TK, Selsted ME, Ouellette AJ. Structure-activity determinants in paneth cell alpha-defensins: loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions J Biol Chem. 2004 Mar 19;279(12):11976-83._x000D_ 4: Rosengren KJ, Daly NL, Fornander LM, Jönsson LM, Shirafuji Y, Qu X, Vogel HJ, Ouellette AJ, Craik DJ. Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4 J Biol Chem. 2006 Sep 22;281(38):28068-78._x000D_ 5: Tomisawa S, Sato Y, Kamiya M, Kumaki Y, Kikukawa T, Kawano K, Demura M, Nakamura K, Ayabe T, Aizawa T. Efficient production of a correctly folded mouse α-defensin, cryptdin-4, by refolding during inclusion body solubilization Protein Expr Purif. 2015 Aug;112:21-8._x000D_ 6: Mishra A, Tai KP, Schmidt NW, Ouellette AJ, Wong GC. Small-angle X-ray scattering studies of peptide-lipid interactions using the mouse paneth cell α-defensin cryptdin-4 Methods Enzymol. 2011;492:127-49._x000D_ 7: Maemoto A, Qu X, Rosengren KJ, Tanabe H, Henschen-Edman A, Craik DJ, Ouellette AJ. Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4 J Biol Chem. 2004 Oct 15;279(42):44188-96._x000D_ 8: Li Q, Zhang Z, Chen X, Wang B, Zhou Z, Yan L, Jiang J. [The change of cryptdin-4 mRNA expression in the intestine of mouse with experimental pancreatitis] Sichuan Da Xue Xue Bao Yi Xue Ban. 2003 Jan;34(1):92-4._x000D_ 9: Figueredo SM, Weeks CS, Young SK, Ouellette AJ. Anionic amino acids near the pro-alpha-defensin N terminus mediate inhibition of bactericidal activity in mouse pro-cryptdin-4 J Biol Chem. 2009 Mar 13;284(11):6826-31._x000D_ 10: Längst N, Adler J, Kuret A, Peter A, Ruth P, Boldt K, Lukowski R. Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE(-/-) Mouse Model Cells. 2022 Apr 17;11(8):1364. _x000D_ _x000D_ Products Related to Cryptdin-4 (Mouse) can be found at Peptides

Catalog Number: MDP0853 (100 ug)

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