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FFN246

CAT: 0804-HY-149170-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149170-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation[1].
CAS Number
2210244-83-8
UNSPSC
12171500
Target
5-HT Receptor; Monoamine Transporter
Type
Dye Reagents
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ffn246.html
Purity
99.79
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; adjust pH to 1 with 1 M HCl; heat to 60°C)
Smiles
O=C1C2=CC(CCN)=CC=C2NC3=C1C(F)=CC=C3
Molecular Formula
C15H13FN2O
Molecular Weight
256.27
References & Citations
[1]Henke A, et al. Toward Serotonin Fluorescent False Neurotransmitters: Development of Fluorescent Dual Serotonin and Vesicular Monoamine Transporter Substrates for Visualizing Serotonin Neurons. ACS Chem Neurosci. 2018;9 (5) :925-934.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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