2'-Deoxyuridine-13C,15N2

2'-Deoxyuridine-13C,15N2

• CAS Number: 369656-76-8
• UNSPSC Description: 2'-Deoxyuridine-13C,15N2 is the 13C and 15N labeled 2'-Deoxyuridine[1]. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine[2].
• Target Antigen: Endogenous Metabolite
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/2-deoxyuridine-13c-15n2.html
• Purity: 98.08
• Solubility: 10 mM in DMSO
• Smiles: O=[13C]1[15N](C=CC([15NH]1)=O)[C@]2([H])O[C@@H]([C@H](C2)O)CO
• Molecular Weight: 231.18
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Reidy JA, et al. Deoxyuridine increases folate-sensitive fragile site expression in human lymphocytes. Am J Med Genet. 1987 Jan;26(1):1-5.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported