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GDP366

CAT: 0804-HY-U00177-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00177-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GDP366, a dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells.
CAS Number
501698-03-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Survivin
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/GDP366.html
Purity
99.80
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=CC(C)=C1)NC2=CC=C(C3=CSC4=NC=NC(N)=C43)C=C2
Molecular Formula
C20H17N5OS
Molecular Weight
375.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Shi X, et al. GDP366, a novel small molecule dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. Cancer Biol Ther. 2010 Apr 15;9 (8) :640-50.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
BA3518-5GDP366

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