Trihexyphenidyl (hydrochloride) (Standard)

Trihexyphenidyl (hydrochloride) (Standard)

• CAS Number: 52-49-3
• UNSPSC Description: Trihexyphenidyl (hydrochloride) (Standard) is the analytical standard of Trihexyphenidyl (hydrochloride). This product is intended for research and analytical applications. Trihexyphenidyl hydrochloride is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl hydrochloride shows anticholinergic activity, and can be used for Parkinson syndrome or dystonia research[1][2][3].
• Target Antigen: Cholinesterase (ChE); mAChR
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/trihexyphenidyl-hydrochloride-standard.html
• Smiles: OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCCC3.[H]Cl
• Molecular Weight: 337.93
• References & Citations: [1]Giachetti A, et al. Binding and functional profiles of the selective M1 muscarinic receptor antagonists trihexyphenidyl and dicyclomine. Br J Pharmacol. 1986 Sep;89(1):83-90. |[2]Dayan N, Touitou E. Carriers for skin delivery of trihexyphenidyl HCl: ethosomes vs. liposomes. Biomaterials. 2000 Sep;21(18):1879-85.|[3]Jilani TN, et al. Trihexyphenidyl. 2022 Feb 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–.
• Shipping Conditions: Room temperature