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Trihexyphenidyl

CAT: 0804-HY-B1277ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B1277ASize:1 Each
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Description
Trihexyphenidyl is a potent and selective M1 muscarinic receptor antagonist. Trihexyphenidyl shows anticholinergic activity, and can be used for Parkinson syndrome or dystonia research[1][2].
CAS Number
144-11-6
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Cholinesterase (ChE) ; mAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trihexyphenidyl.html
Solubility
10 mM in DMSO
Smiles
OC(C1=CC=CC=C1)(C2CCCCC2)CCN3CCCCC3
Molecular Formula
C20H31NO
Molecular Weight
301.47
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Giachetti A, et al. Binding and functional profiles of the selective M1 muscarinic receptor antagonists trihexyphenidyl and dicyclomine. Br J Pharmacol. 1986 Sep;89 (1) :83-90. |[2]Jilani TN, et al. Trihexyphenidyl. 2022 Feb 27. In: StatPearls [Internet]. Treasure Island (FL) : StatPearls Publishing; 2022 Jan–.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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