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Bavachalcone (Standard)

CAT: 0804-HY-N0231RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N0231RSize:1 Each
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Description
Bavachalcone (Standard) is the analytical standard of Bavachalcone. This product is intended for research and analytical applications. Bavachalcone is a potent inducer of apoptosis. Bavachalcone exerts anticancer activity by promoting autophagy and apoptosis in HepG2 cells. Bavachalcone acts as an anti-neuroinflammatory and antidepressant through the NF-κB pathway. Bavachalcone inhibits osteoclasts by interfering with ERK and Akt signaling pathways and the expression of c-Fos and NFATc1. Bavachalcone exhibits a significant inhibitory effect on baculovirus-expressed BACE-1 in vitro[1][2][3][4].
CAS Number
28448-85-3
Product Name Alternative
Broussochalcone B (Standard)
UNSPSC
12352005
Target
Antibiotic; Apoptosis; Autophagy; Bacterial; NF-κB; PERK; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; NF-κB; Others
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bavachalcone-standard.html
Smiles
O=C(C1=CC(C/C=C(C)\C)=C(O)C=C1O)/C=C/C2=CC=C(O)C=C2
Molecular Formula
C20H20O4
Molecular Weight
324.37
References & Citations
[1]Park CK, et al. Bavachalcone inhibits osteoclast differentiation through suppression of NFATc1 induction by RANKL. Biochem Pharmacol. 2008 Jun 1;75 (11) :2175-82.|[2]Choi YH, et al. In vitro BACE-1 inhibitory phenolic components from the seeds of Psoralea corylifolia. Planta Med. 2008 Sep;74 (11) :1405-8.|[3]Shan L, et al. Comparison of the Inhibitory Potential of Bavachalcone and Corylin against UDP-Glucuronosyltransferases. Evid Based Complement Alternat Med. 2014;2014:958937.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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