Octanoic acid

• Description :

  Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoic acid is also a tremor-suppressing agent[1][2].

• Product Name Alternative :

  Caprylic acid

• UNSPSC :

  12352211

• Hazard Statement :

  H314, H412

• Target :

  Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/1-Heptanecarboxylic_acid.html

• Purity :

  99.85

• Solubility :

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CCCCCCCC(O)=O

• Molecular Formula :

  C8H16O2

• Molecular Weight :

  144.21

• Precautions :

  H314, H412

• References & Citations :

  [1]Nahab FB, et al. Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor. Neurotherapeutics. 2012 Jul;9 (3) :635-8.|[2]Joniec-Maciejak I, et al. Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease. Pharmacol Rep. 2018 Oct;70 (5) :988-992. |[3]Kadota Y, et al. Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. Metabolism. 2015 Sep;64 (9) :1157-64. |[4]Leem J, et al. Octanoic acid potentiates glucose-stimulated insulin secretion and expression of glucokinase through the olfactory receptor in pancreatic β-cells. Biochem Biophys Res Commun. 2018 Sep 3;503 (1) :278-284.|[5]Kamata Y, et al. Induction of neurite outgrowth in PC12 cells by the medium-chain fatty acid octanoic acid. Neuroscience. 2007 May 25;146 (3) :1073-81.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Natural Products

• Clinical Information :

  Phase 1

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [124-07-2]