2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one

• CAS Number: 1809980-25-3
• UNSPSC Description: 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities[1].
• Target Antigen: Dipeptidyl Peptidase
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/2-methoxy-5-acetoxy-fruranogermacr-1-10-en-6-one.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@@H]([C@@H](C1)C)OC(C)=O)C(C(C)=CO2)=C2C/C(C)=C/[C@@H]1OC
• Molecular Weight: 320.38
• References & Citations: [1]Alexandra Quek, et al. Identification of Dipeptidyl Peptidase-4 and α-Amylase Inhibitors from Melicope glabra (Blume) T. G. Hartley (Rutaceae) Using Liquid Chromatography Tandem Mass Spectrometry, In Vitro and In Silico Methods. Molecules. 2021 Jan; 26(1): 1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported