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NOTCH1 Human Gene Knockout Kit (CRISPR)

CAT: 0937-KN211365RBSize: 1 KitDry Ice: NoHazardous: No
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CAT#:0937-KN211365RBSize:1 Kit
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Description
NOTCH1 - human gene knockout kit via CRISPR, HDR mediated
UniProt
P46531
Gene Location
4851
Stability
The primer mix is stable for one year from date of shipping.
Shipping Conditions
Store at -20°C.
Storage Conditions
Store at -20°C.
Symbol
NOTCH1

UniProtKB · P46531

Neurogenic locus notch homolog protein 1

NOTC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46531
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 1, hN1
EC number
—
Processing
Precursor
Secondary accessions
Q59ED8, Q5SXM3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Biological process

AngiogenesisDifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

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