Xipamide

• Description :

  Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  Anion Exchangers

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/xipamide.html

• Purity :

  99.74

• Solubility :

  DMSO : 250 mg/mL (ultrasonic)

• Smiles :

  O=C(NC1=C(C)C=CC=C1C)C2=CC(S(=O)(N)=O)=C(Cl)C=C2O

• Molecular Formula :

  C15H15ClN2O4S

• Molecular Weight :

  354.81

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Prichard BN, et al. Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1985 Oct;30 (4) :313-32.|[2]Hannaert P, et al. Beneficial effects of xipamide on pH and Ca2+ ions of cardiac cells. Arch Mal Coeur Vaiss. 1990 Jul;83 (8) :1271-4.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [14293-44-8]