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Human COMT activation kit by CRISPRa

CAT: 0937-GA100924Size: 1 KitDry Ice: NoHazardous: No
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CAT#:0937-GA100924Size:1 Kit
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Description
COMT CRISPRa kit - CRISPR gene activation of human catechol-O-methyltransferase
Synonyms
OR5A1P, OR11-249, OST181
UniProt
P21964
Gene Location
1312
Tag
Myc-DDK
Stability
AAV is stable for 1 year when stored at -80°C (long-term storage) or 2-3 weeks when stored at -20°C (short-term storage). Thaw the vial of AAV on ice prior to use and keep it on ice during the experiment. Thawed AAV can be stored at 4°C for 1-2 weeks. Whenever possible, particles shoµLd be aliquoted into single use portions to avoid repeated freeze/thaw cycles. Please aliquot at least 10µL per tube and use low protein binding tubes to avoid loss of virus.
Symbol
COMT

UniProtKB · P21964

Catechol O-methyltransferase

COMT_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P21964
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
COMT
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.1.1.6
Processing
—
Secondary accessions
A8MPV9, Q6IB07, Q6ICE6, Q9BWC7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative initiation

Biological process

Catecholamine metabolismLipid metabolismNeurotransmitter degradation

Cellular component

Cell membraneCytoplasmMembrane

Ligand

MagnesiumMetal-bindingS-adenosyl-L-methionine

Molecular function

MethyltransferaseTransferase

PTM

Phosphoprotein

Disease

Schizophrenia

Domain

Signal-anchorTransmembraneTransmembrane helix

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