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Azelaic acid

CAT: 0804-HY-B0704-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-B0704-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Azelaic acid is a nine-carbon dicarboxylic acid. Azelaic acid has antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis through inhibition of microbial cellular prorein synthesis. Azelaic acid has hypopigmentation action resulting from its ability to scavenge free radicals[1][2].
CAS Number
123-99-9
Product Name Alternative
Nonanedioic acid
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Endogenous Metabolite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Azelaic-acid.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OC(CCCCCCCC(O)=O)=O
Molecular Formula
C9H16O4
Molecular Weight
188.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Jung HW, et al. Priming in systemic plant immunity. Science. 2009 Apr 3;324 (5923) :89-91.|[2]Liu RH, et al. Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. Arch Dermatol. 2006 Aug;142 (8) :1047-52.|[3]J P Leeming, et al. The in vitro antimicrobial effect of azelaic acid. Br J Dermatol. 1986 Nov;115 (5) :551-6.|[4]Harald Gollnick, et al. Azelaic acid 15% gel in the treatment of rosacea. |[5]Dongdong Zhang, et al. Azelaic Acid Exerts Antileukemia Effects against Acute Myeloid Leukemia by Regulating the Prdxs/ROS Signaling Pathway. Oxid Med Cell Longev. 2020 Dec 23:2020:1295984.|[6]L Lemic-Stojcevic, et al. Dongdong Zhang, et al. Effect of azelaic acid on melanoma cells in culture. Exp Dermatol. 1995 Apr;4 (2) :79-81.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite

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