Crk p38 Recombinant Rabbit Monoclonal Antibody [JE38-60]

Crk p38 Recombinant Rabbit Monoclonal Antibody [JE38-60]

• Description: This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
• Product Name Alternative: Adapter molecule crk antibody Avian sarcoma virus CT10 (v crk) oncogene homolog antibody CRK antibody CRK isoform 2 antibody CRK isoform II antibody CRK_HUMAN antibody CRKII antibody FLJ38130 antibody OTTHUMP00000115366 antibody OTTHUMP00000198330 antibody p38 antibody Proto oncogene C crk antibody Proto-oncogene C-crk antibody v crk avian sarcoma virus CT10 oncogene homolog antibody v crk sarcoma virus CT10 oncogene homolog antibody v crk sarcoma virus CT10 oncogene homolog (avian) antibody
• Abbreviation: Adapter molecule crk Proto-oncogene c-Crk p38 CRK
• CAS Number: 9000-83-3
• Swiss Prot: P46108 Human, Q63768 Rat
• Cellular Locus: Cell membrane. Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Rat
• Immunogen: Recombinant protein within Human Crk p38 aa 1-100 / 304.
• Isotype: IgG
• Clone: JE38-60
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB
• Positive Control: HeLa cell lysate, HepG2 cell lysate, C6 cell lysate, PC-12 cell lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 34 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes