HPGDS inhibitor 1
CAT:
804-HY-10439-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HPGDS inhibitor 1
- CAS Number: 1033836-12-2
- UNSPSC Description: HPGDS inhibitor 1 is a potent, selective and orally active Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50s of 0.6 nM and 32 nM in enzyme and cellular assays, respectively. HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5-LOX[1].
- Target Antigen: PGE synthase
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/hpgds-inhibitor-1.html
- Purity: 99.04
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C(NC1CCN(CC(F)(F)F)CC1)C2=CC=C(C3=CC=CC(F)=C3)N=C2
- Molecular Weight: 381.37
- References & Citations: [1]Chris P Carron, et al. Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS). ACS Med Chem Lett. 2010 Feb 2;1(2):59-63.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported