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Neoandrographolide (Standard)

CAT: 0804-HY-N0721RSize: 1 EachDry Ice: NoHazardous: No
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Description
Neoandrographolide (Standard) is the analytical standard of Neoandrographolide. This product is intended for research and analytical applications. Neoandrographolide is a diterpenoid compound isolated from Andrographis paniculata. Neoandrographolide inhibits osteoclasts differentiation and bone resorption through inhibition of MAPK/NF-κB/PI3K/AKT/GSK3β/PPAR/CAMK signaling pathway. Neoandrographolide inhibits apoptosis in rat embryonic ventricular cardiomyocytes. Neoandrographolide inhibits iNOS and the generation of ROS, activates eNOS, exhibiting anti-inflammatory and hypolipidemic activity[1][2][3][4][5].
CAS Number
27215-14-1
Product Name Alternative
Neoandrographiside (Standard)
UNSPSC
12352005
Target
Apoptosis; ERK; GSK-3; JNK; NF-κB; NO Synthase; p38 MAPK; PI3K; PPAR; Reactive Oxygen Species (ROS) ; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Others; PI3K/Akt/mTOR; Stem Cell/Wnt; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/neoandrographolide-standard.html
Smiles
C[C@@]([C@@H]1CCC2=CCOC2=O)(CCC3)[C@@](CCC1=C)([H])[C@]3(C)CO[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO
Molecular Formula
C26H40O8
Molecular Weight
480.59
References & Citations
[1]Tao Yang, et al. Hypolipidemic Effects of Andrographolide and Neoandrographolide in Mice and Rats. Phytotherapy Research Volume 27, Issue 4, pages 618–623, April 2013
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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TRC-N389913-25MGNeoandrographolide
A14754-25Neoandrographolide 25mg
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A14754-100Neoandrographolide 100mg

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