α-Triglycidyl isocyanurate

α-Triglycidyl isocyanurate

• CAS Number: 59653-73-5
• UNSPSC Description: α-Triglycidyl isocyanurate (Teroxirone) is an antitumor compound with activity to inhibit DNA replication. α-Triglycidyl isocyanurate exerts its anticancer effect by alkylating and cross-linking DNA. α-Triglycidyl isocyanurate is relatively stable in fresh human plasma and whole blood, showing good biocompatibility. The metabolism of α-Triglycidyl isocyanurate mainly occurs in rat liver and is metabolized through an NADPH-independent pathway. The cytotoxicity of α-Triglycidyl isocyanurate can be partially restored under specific conditions, suggesting the complexity of its metabolic pathway[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/α-triglycidyl-isocyanurate.html
• Smiles: O=C(N(C(N(C1=O)C[C@H]2CO2)=O)C[C@@H]3CO3)N1C[C@@H]4CO4
• Molecular Weight: 297.26
• References & Citations: [1]Pharmacological characterization of teroxirone, a triepoxide antitumor agent, in rats, rabbits, and humans
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported