Triglycidyl isocyanurate
CAT:
804-HY-W011434-03
Size:
10 g
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Triglycidyl isocyanurate
- CAS Number: 2451-62-9
- UNSPSC Description: Triglycidyl isocyanurate (TGIC; Teroxirone) is a triazene triepoxide with antiangiogenic and antineoplastic activities. Triglycidyl isocyanurate inhibits the growth of non-small-cell-lung cancer cells via?p53 activation. Triglycidyl isocyanurate induces cell apoptosis. Triglycidyl isocyanurate can be used for cancer research[1][2].
- Target Antigen: Apoptosis; MDM-2/p53
- Type: Reference compound
- Related Pathways: Apoptosis
- Applications: COVID-19-immunoregulation
- Field of Research: Cancer; Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/triglycidyl-isocyanurate.html
- Purity: 98.0
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C(N(C1=O)CC2CO2)N(C(N1CC3CO3)=O)CC4CO4
- Molecular Weight: 297.26
- References & Citations: [1]Yu-Ling Ni, et al. Teroxirone motivates apoptotic death in tumorspheres of human lung cancer cells. Chem Biol Interact. 2018 Aug 1;291:137-143|[2]Seung-Hun Kim, et al. Teroxirone suppresses growth and motility of human hepatocellular carcinoma cells.Biomed Pharmacother. 2018 Mar;99:997-1008
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported