RegisterLogin

Granisetron

CAT: 0804-HY-B0071-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0071-01Size:25 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.
CAS Number
[109889-09-0]
Product Name Alternative
BRL 43694
UNSPSC
12352005
Hazard Statement
H302, H319, H412
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Granisetron.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN1N=C(C(N[C@H]2C[C@H](N3C)CCC[C@H]3C2)=O)C4=CC=CC=C41
Molecular Formula
C18H24N4O
Molecular Weight
312.41
Precautions
H302, H319, H412
References & Citations
[1]Sanger GJ, Nelson DR. Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron) . Eur J Pharmacol. 1989 Jan 10;159 (2) :113-24.|[2]Maleki-Dizaji N, Eteraf-Oskouei T, Fakhrjou A, The effects of 5HT3 receptor antagonist granisetron on inflammatory parameters and angiogenesis in the air-pouch model of inflammation. Int Immunopharmacol. 2010 Sep;10 (9) :1010-6.|[3]Boccia RV, Gordan LN, Clark G, Efficacy and tolerability of transdermal granisetron for the control of chemotherapy-induced nausea and vomiting associated with moderately and highly emetogenic multi-day chemotherapy: a randomized, double-blind, phase III study. Support Care Cancer. 2011 Oct;19 (10) :1609-17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Lactoferrin

Related Products

CatalogName

Alternative Products

CatalogName
RM-G121915-01Granisetron
sc-218455Exo-Granisetron (Granisetron Impurity F)
TRC-D292038-5MG1-Desmethyl Granisetron (Granisetron Impurity B)
255398-01Granisetron hydrochloride
TRC-G780003-25MGGranisetron-d3
100421Granisetron HCl
A15096-50Granisetron 50mg
A15096-100Granisetron 100mg

Popular Products