Atomoxetine-d5 (hydrochloride)

Atomoxetine-d5 (hydrochloride)

• UNSPSC Description: Atomoxetine-d5 (hydrochloride) is the deuterium labeled Atomoxetine hydrochloride. Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively)[1][2].
• Target Antigen: Adrenergic Receptor; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
• Field of Research: Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: CC1=CC=CC=C1O[C@@H](C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])CCNC.[H]Cl
• Molecular Weight: 296.85
• References & Citations: [1]Owens MJ, et al. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther. 1997 Dec;283(3):1305-22.|[2]Owens MJ, et al. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther. 1997 Dec;283(3):1305-22. PMID: 9400006.. . .
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported