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Bis-propargyl-PEG1

CAT: 0804-HY-140038-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-140038-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bis-propargyl-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-propargyl-PEG1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
40842-04-4
UNSPSC
12352211
Hazard Statement
H226
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-propargyl-peg1.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C#CCOCCOCC#C
Molecular Formula
C8H10O2
Molecular Weight
138.16
Precautions
H226
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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