TAPI-2

CAT: 1568-C12681-1mgSize: 1 mgDry Ice: NoHazardous: No

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CAT#:1568-C12681-1mgSize:1 mg

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CAS Number

187034-31-7

Synonyms

TNF Protease Inhibitor 2

Additionnal Information

TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP. TAPI-2 blocks the entry of infectious SARS-CoV.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

Chemical Information

N1-((S)-1-(((S)-1-((2-aminoethyl)amino)-1-oxopropan-2-yl)amino)-3,3-dimethyl-1-oxobutan-2-yl)-N4-hydroxy-2-isobutylsuccinamide

N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide Acetic Acid is a dipeptide.

CAS Number	187034-31-7
PubChem CID	10093303
IUPAC Name	N-[(2S)-1-[[(2S)-1-(2-aminoethylamino)-1-oxopropan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide
Molecular Formula	C19H37N5O5
Molecular Weight	415.5
XLogP	-0.1
Topological Polar Surface Area	163
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	12
Heavy Atom Count	29
Formal Charge	0
Complexity	574

SMILES

C[C@@H](C(=O)NCCN)NC(=O)[C@H](C(C)(C)C)NC(=O)C(CC(C)C)CC(=O)NO

InChI

InChI=1S/C19H37N5O5/c1-11(2)9-13(10-14(25)24-29)17(27)23-15(19(4,5)6)18(28)22-12(3)16(26)21-8-7-20/h11-13,15,29H,7-10,20H2,1-6H3,(H,21,26)(H,22,28)(H,23,27)(H,24,25)/t12-,13?,15+/m0/s1

InChIKey

LMIQCBIEAHJAMZ-RMTCENKZSA-N

Chemical Structure

2D Structure

CAS: 187034-31-7

CID: 10093303

Formula: C19H37N5O5

MW: 415.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	415.5
XLogP3	-0.1
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	12
Exact Mass	415.27946930
Monoisotopic Mass	415.27946930
Topological Polar Surface Area	163 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	574
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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MBS406190-01	TAPI-2
MBS5764101	TAPI 2
HY-100211A	(R) -TAPI-2
A14009-5	TAPI-2 5mg
A14009-2	TAPI-2 2mg
HY-100211R	TAPI-2 (Standard)
A14009-1	TAPI-2 1mg
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A14009-10	TAPI-2 10mg
A14009-100	TAPI-2 100mg

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