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GW284543 (UNC10225170)

CAT: 1568-C12082-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C12082-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
790186-68-4
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
COC1=CC2=C (C=C1OC) C (=CC=N2) NC3=CC (=CC=C3) OC4=CC=CC=C4
Molecular Formula
C23H20N2O3
Additionnal Information
GW284543 (UNC10225170), a MEK5-selective inhibitor, inhibits MEK5 in a dose-dependently way as determined by reductions in pERK5, and decreases endogenous MYC protein.
Storage Conditions
3 years -20°C powder

Chemical Information

6,7-dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine
CAS Number790186-68-4
PubChem CID44531022
IUPAC Name6,7-dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine
Molecular FormulaC23H20N2O3
Molecular Weight372.4
XLogP5.2
Topological Polar Surface Area52.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count28
Formal Charge0
Complexity471
SMILES
COC1=CC2=C(C=CN=C2C=C1OC)NC3=CC(=CC=C3)OC4=CC=CC=C4
InChI
InChI=1S/C23H20N2O3/c1-26-22-14-19-20(11-12-24-21(19)15-23(22)27-2)25-16-7-6-10-18(13-16)28-17-8-4-3-5-9-17/h3-15H,1-2H3,(H,24,25)
InChIKey
LEEMRFWMAIVHQY-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6,7-dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine
CAS: 790186-68-4
CID: 44531022
Formula: C23H20N2O3
MW: 372.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight372.4
XLogP35.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass372.14739250
Monoisotopic Mass372.14739250
Topological Polar Surface Area52.6 Ų
Heavy Atom Count28
Formal Charge0
Complexity471
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
S6641-5mgGW284543 (UNC10225170)
T7610-01GW284543
A18808-100GW284543 100mg
A18808-50GW284543 50mg
A18808-5GW284543 5mg
A18808-10GW284543 10mg
A18808-25GW284543 25mg
HY-114189AGW284543 (hydrochloride)
A18808-1GW284543 1mg
A18808-10mM-DGW284543 10mM * 1mL in DMSO

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