Products for Research Use Only
RegisterLogin

HFSH-β- (33-53) (TFA)

CAT: 0804-HY-P3343A-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P3343A-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HFSH-β- (33-53) TFA, a thiol-containing peptide which corresponds to a second FSH receptor-binding domain, is a FSHR (follicle-stimulating hormone receptor) antagonist. hFSH-β- (33-53) TFA inhibits binding of FSH to receptor and is a partial agonist of estradiol synthesis in Sertoli cells[1][2][3].
UNSPSC
12352209
Target
Estrogen Receptor/ERR
Type
Peptides
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hfsh-β-33-53-tfa.html
Purity
99.16
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(CCC1)C([C@H](CC(O)=O)NC([C@H](CCCCN)NC([C@@H](NC([C@H](C(C)C)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H]([C@H](O)C)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(N[C@@H]([C@H](O)C)C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C115H183N31O32S.xC2HF3O2
Molecular Weight
2543.94 (free acid)
References & Citations
[1]Grasso P, et al. A synthetic peptide corresponding to hFSH-beta- (81-95) has thioredoxin-like activity. Mol Cell Endocrinol. 1991;78 (3) :163-170. |[2]Xu Y, et al. Pilot study of a novel (18) F-labeled FSHR probe for tumor imaging. Mol Imaging Biol. 2014;16 (4) :578-585. |[3]Santa-Coloma TA, et al. Serine analogues of hFSH-beta- (33-53) and hFSH-beta- (81-95) inhibit hFSH binding to receptor. Biochem Biophys Res Commun. 1992;184 (3) :1273-1279.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P1341AOXA (17-33) (TFA)
HY-P0323A-01GP (33-41) (TFA)
HY-P3793Amyloid β-Protein (33-42) (TFA)
HY-P1585A-01Gp100 (25-33), human (TFA)
HY-P1297ACRF (6-33) (human) (TFA)
HY-P2506A-01Gp100 (25-33), mouse (TFA)
HY-P1244A-01Secretin (33-59), rat (TFA)
HY-P1019A[Ala1, ​3, ​11, ​15]​-​Endothelin (53-63) (TFA)
HY-P1815A-01C-Type Natriuretic Peptide (1-53), human (TFA)
HY-P2625S1GLP-2 (3-33) (Leu-13C6,15N) (TFA)

Alternative Products

CatalogName
GTR19036339HFSH-β- (33-53) (TFA)
MBS5818131hFSH-beta-(33-53)(TFA)
GTR19035834-01PMX-53 TFA
UIA63975-01PMX 53 TFA
T75766-01GP (33-41) TFA
MBS5817827OXA (17-33) TFA
T75893-01CRF (6-33) (human) TFA
MBS5817769Secretin (33-59), rat TFA
MBS5817798CRF (6-33)(human) TFA
GTR19144796-01Gp100 (25-33), mouse TFA

Popular Products