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Danusertib (PHA-739358)

CAT: 1568-C16114-2mgSize: 2 mgDry Ice: YesHazardous: No
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CAT#:1568-C16114-2mgSize:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
827318-97-8
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CN1CCN (CC1) C2=CC=C (C=C2) C (=O) NC3=NNC4=C3CN (C4) C (=O) C (C5=CC=CC=C5) OC
Molecular Formula
C26H30N6O3
Additionnal Information
Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc. Danusertib induces apoptosis, cell cycle arrest, and autophagy. Phase 2.
Storage Conditions
2 years -80 in solvent

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