Danusertib

• Target :

  Autophagy|||Aurora Kinase|||c-RET|||FGFR|||Bcr-Abl|||Trk receptor

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Autophagy|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Angiogenesis|||Apoptosis

• Purity :

  0.9879

• Bioactivity :

  Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Danusertib binds to and inhibits the Aurora kinases, which may result in cell growth arrest and apoptosis in tumor cells in which Aurora kinases are overexpressed.

• Smiles :

  CO[C@@H](C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1)c1ccccc1

• Molecular Formula :

  C26H30N6O3

• Molecular Weight :

  474.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  827318-97-8