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CP-100356 hydrochloride

CAT: 1568-C03651-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:1568-C03651-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
142715-48-8
Target
BCRP
Applications
Transmembrane Transporters
Molecular Formula
C31H36N4O6.ClH
Additionnal Information
CP-100356 hydrochloride is an orally active dual inhibitor of MDR1 (P-gp) and BCRP, with IC50 of ∼0.5 μM for MDR1-mediated calcein-AM transport inhibition and ∼1.5 μM for BCRP-mediated prazosin transport inhibition. It is also a weak inhibitor of OATP1B1 (IC50 ∼ 66 μM) .

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