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KHK-6

CAT: 1568-C03299-250mgSize: 250 mgDry Ice: NoHazardous: No
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CAT#:1568-C03299-250mgSize:250 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
MAP4K
Applications
MAPK
Additionnal Information
KHK-6 is a potent ATP-competitive inhibitor of HPK1 kinase activity with an IC50 value of 20 nM. It significantly enhances CD3/CD28-induced production of cytokines by downregulating the HPK1-SLP-76 signaling cascade in the TCR signaling pathway.

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