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Hck-IN-1

CAT: 1568-C02200-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C02200-5mgSize:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1473404-51-1
Target
Others
Applications
Others
Smiles
NC (=S) [N]1N=C (C2=CC=C (C=C2) [N; v5] (=O) =O) C (=C1O) N=NC3=CC (=CC=C3) Cl
Molecular Formula
C16H11ClN6O3S
Additionnal Information
Hck-IN-1, a selective Nef-dependent Hck inhibitor, blocks the kinase activity of the Nef:Hck complex in vitro with an IC50 value of 2.8 μM, whereas its activity against Hck alone is >20 μM, also blocks wild-type HIV-1 replication with an IC50 value in the 100-300 nM range.
Storage Conditions
3 years -20°C powder