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Talabostat

CAT: 0926-ZFA68277-02Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0926-ZFA68277-02Size:10 mg
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CAS Number
149682-77-9
MDL Number
MFCD09833674
Smiles
B (C1CCCN1C (=O) C (C (C) C) N) (O) O
Molecular Formula
C9H19BN2O3
Molecular Weight
214.07 g/mol
Controlled
No

Chemical Information

Talabostat

Talabostat is a small molecule with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines.

CAS Number149682-77-9
PubChem CID6918572
IUPAC Name[(2R)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid
Molecular FormulaC9H19BN2O3
Molecular Weight214.07
Topological Polar Surface Area86.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count15
Formal Charge0
Complexity235
SMILES
B([C@@H]1CCCN1C(=O)[C@H](C(C)C)N)(O)O
InChI
InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1
InChIKey
FKCMADOPPWWGNZ-YUMQZZPRSA-N
Chemical Structure
2D Structure
2D structure of Talabostat
CAS: 149682-77-9
CID: 6918572
Formula: C9H19BN2O3
MW: 214.07
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight214.07
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass214.1488726
Monoisotopic Mass214.1488726
Topological Polar Surface Area86.8 Ų
Heavy Atom Count15
Formal Charge0
Complexity235
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-13233-01Talabostat
466792-01Talabostat Mesylate
GW8231-50mgTalabostat . mesylate
A14079-100Talabostat 100mg
A14079-50Talabostat 50mg
A14079-10Talabostat 10mg
HY-13233A-01Talabostat (mesylate)
A14079-5Talabostat 5mg

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