Robinetin

CAT: 0804-HY-N1347Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N1347Size:5 mg
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Description
Robinetin (3,3',4',5',7-Pentahydroxyflavone), a naturally occurring flavonoid with remarkable ‘two color’ intrinsic fluorescence properties, has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin also can inhibit lipid peroxidation and protein glycosylation[1][2][3][4][5].
CAS Number
[490-31-3]
Product Name Alternative
3,3',4',5',7-Pentahydroxyflavone
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Bacterial; Fungal; HIV Integrase
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/robinetin.html
Purity
98.15
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
O=C1C(O)=C(C2=CC(O)=C(O)C(O)=C2)OC3=CC(O)=CC=C13
Molecular Formula
C15H10O7
Molecular Weight
302.24
Precautions
H315, H319, H335
References & Citations
[1]Fesen MR, et, al. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem Pharmacol. 1994 Aug 3;48 (3) :595-608.|[2]Cushnie TPT, et, al. Antimicrobial activity of flavonoids. Int J Antimicrob Agents. 2005 Nov;26 (5) :343-56.|[3]Chaudhuri S, et, al. Binding of the bioflavonoid robinetin with model membranes and hemoglobin: Inhibition of lipid peroxidation and protein glycosylation. J Photochem Photobiol B. 2010 Jan 21;98 (1) :12-9.|[4]Birt DF, et, al. Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol. Carcinogenesis. 1986 Jun;7 (6) :959-63.|[5]Manrique-de-la-Cuba MF, et, al. Theoretical study of the antioxidant capacity of the flavonoids present in the Annona muricata (Soursop) leaves. J Mol Model. 2019 Jun 25;25 (7) :200.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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