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CSN5i-3

CAT: 0957-E1219-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E1219-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2375740-98-8
Smiles
O=C (C1=CC (C (F) F) =NN1C (C) C) NC2=CC (C3=CC=CC=C3) =C ([C@@H]4N5C (CCC[C@@H]4O) =CN=C5) C=C2
Molecular Formula
C28H29F2N5O2
Additionnal Information
CSN5i-3 is a selective, orally bioavailable CSN5/Jab1 inhibitor that demonstrates potent activity in suppressing CSN-mediated Cul1 deneddylation, exhibiting an IC50 of 5.8 nM.

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