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ALR2-IN-5

CAT: 0804-HY-162758Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162758Size:1 Each
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Description
ALR2-IN-5 (Compound 10a) is an inhibitor of ALR2 with an IC50 value of 99.29 nM. ALR2-IN-5 exhibits hypoglycemic effects and can be utilized in research related to diabetes[1].
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/alr2-in-5.html
Smiles
CC1=CC=C(S(OC2=CC=C(C(C(C#N)=C(N)N3C4=NC=CS4)=C(C#N)C3=O)C=C2)(=O)=O)C=C1
Molecular Formula
C23H15N5O4S2
Molecular Weight
489.53
References & Citations
[1]Said GE, et al. Development of non-acidic 4-methylbenzenesulfonate-based aldose reductase inhibitors; Design, Synthesis, Biological evaluation and in-silicostudies. Bioorg Chem. 2024 Jul 22;151:107666.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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