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BSO

CAT: 0957-S9728-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-S9728-1gSize:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
83730-53-4
Synonyms
L-Buthionine sulfoximine, l-BSO
Target
γGCS
Applications
Metabolism
Smiles
CCCC[S] (=N) (=O) CCC (N) C (O) =O
Molecular Formula
C8H18N2O3S
Additionnal Information
BSO is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase (γ-glutamylcysteine synthetase, γ-GCS) and depletes cellular glutathione levels. The IC50 of BSO on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
Storage Conditions
3 years -20°C powder

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