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TK216

CAT: 0957-S9718-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S9718-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1903783-48-1
Synonyms
ONCT 216, SPH-8216
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
OC1 (CC (=O) C2=CC=C (C=C2) C3CC3) C (=O) NC4=C (Cl) C=CC (=C14) Cl
Molecular Formula
C19H15Cl2NO3
Additionnal Information
TK216 is a potent inhibitor targeting E26 transformation specific (ETS) factors via blocking the protein-protein interaction with RNA helicases. TK216 exhibits antilymphoma activity.
Storage Conditions
3 years -20°C powder

Chemical Information

4,7-Dichloro-3-(2-(4-cyclopropylphenyl)-2-oxoethyl)-3-hydroxyindolin-2-one
CAS Number1903783-48-1
PubChem CID121268274
IUPAC Name4,7-dichloro-3-[2-(4-cyclopropylphenyl)-2-oxoethyl]-3-hydroxy-1H-indol-2-one
Molecular FormulaC19H15Cl2NO3
Molecular Weight376.2
XLogP4.1
Topological Polar Surface Area66.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity559
SMILES
C1CC1C2=CC=C(C=C2)C(=O)CC3(C4=C(C=CC(=C4NC3=O)Cl)Cl)O
InChI
InChI=1S/C19H15Cl2NO3/c20-13-7-8-14(21)17-16(13)19(25,18(24)22-17)9-15(23)12-5-3-11(4-6-12)10-1-2-10/h3-8,10,25H,1-2,9H2,(H,22,24)
InChIKey
ZWHNLSHDLKIXOG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4,7-Dichloro-3-(2-(4-cyclopropylphenyl)-2-oxoethyl)-3-hydroxyindolin-2-one
CAS: 1903783-48-1
CID: 121268274
Formula: C19H15Cl2NO3
MW: 376.2
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight376.2
XLogP34.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass375.0428987
Monoisotopic Mass375.0428987
Topological Polar Surface Area66.4 Ų
Heavy Atom Count25
Formal Charge0
Complexity559
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA3968-5.1TK216
T39329-01(+)-TK216
HY-122903A-01(-) -TK216
HY-122903B-01(+) -TK216
T39330-01(-)-TK216
HY-122903S-01TK216-d4

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