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INT-777

CAT: 0957-S8223-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8223-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1199796-29-6
Synonyms
S-EMCA
Target
GPCR19
Applications
GPCR & G Protein
Smiles
CCC1C2CC (CCC2 (C3CC (C4 (C (C3C1O) CCC4C (C) CC (C) C (=O) O) C) O) C) O
Molecular Formula
C27H46O5
Additionnal Information
INT-777 (S-EMCA) is a potent and selective agonist of TGR5 (GPCR19) with EC50 of 0.18 μM, 3.9 μM and 1.45 μM for TGR5, TGR5 (N76A) and TGR5 (Y89F) respectively.