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TH588

CAT: 0957-S7632-5mgSize: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S7632-5mgSize:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1609960-31-7
Target
MTH1
Applications
DNA Damage/DNA Repair
Smiles
C1CC1NC2=NC (=NC (=C2) C3=C (C (=CC=C3) Cl) Cl) N
Molecular Formula
C13H12Cl2N4
Additionnal Information
TH588 is a potent and selective MTH1 (NUDT1) inhibitor with IC50 of 5 nM. It has no relevant inhibition of any of the other tested proteins at 100 μM, although TH588 showed reasonable selectivity when tested on a much larger panel of 87 enzymes, GPCRs, kinases, ion channels and transporters at 10 μM.
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
B5845-5.1TH588
T60984-01TH588 hydrochloride
A15537-2TH588 2mg
HY-12814ATH588 (hydrochloride)
A15537-25TH588 25mg
A15537-5TH588 5mg
HY-12814RTH588 (Standard)
A15537-100TH588 100mg
A15537-50TH588 50mg
A15537-10TH588 10mg

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