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TH588 (Standard)

CAT: 0804-HY-12814RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12814RSize:1 Each
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Description
TH588 (Standard) is the analytical standard of TH588. This product is intended for research and analytical applications. TH588 is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1 (IC50= 5 nM) .
CAS Number
1609960-31-7
UNSPSC
12352100
Target
DNA/RNA Synthesis; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
NC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC3CC3)=N1
Molecular Formula
C13H12Cl2N4
Molecular Weight
295.17
References & Citations
[1]Gad H, et al. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature. 2014 Apr 10;508 (7495) :215-21.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

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B5845-5.1TH588
T60984-01TH588 hydrochloride
A15537-2TH588 2mg
A15537-100TH588 100mg
A15537-50TH588 50mg
A15537-10TH588 10mg

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