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SEA0400

CAT: 0957-S6920-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S6920-5mgSize:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
223104-29-8
Target
Calcium Channel
Applications
Neuronal Signaling
Smiles
CCOC1=CC=C (OC2=CC=C (OCC3=C (F) C=CC (=C3) F) C=C2) C (=C1) N
Molecular Formula
C21H19F2NO3
Additionnal Information
SEA0400 is a selective and potent inhibitor of the Na+-Ca2+ exchanger (NCX) that inhibits Na+-dependent Ca2+ uptake in cultured neurons, astrocytes, and microglia with IC50 of 33 nM, 5.0 nM and 8.3 nM, respectively. SEA0400 prevents sodium nitroprusside (SNP) from increasing ERK and p38 MAPK phosphorylation and production of reactive oxygen species (ROS) in an extracellular Ca (2+) -dependent manner.
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
A3811-5SEA0400
A15236-100SEA0400 100mg
A15236-5SEA0400 5mg
HY-15515R-01SEA0400 (Standard)
A15236-500SEA0400 500mg
A15236-10SEA0400 10mg
A15236-2SEA0400 2mg
A15236-50SEA0400 50mg
A15236-25SEA0400 25mg
A15236-1SEA0400 1mg

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