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Pemetrexed

CAT: 0957-S5971-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-S5971-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
137281-23-3
Synonyms
LY231514
Target
Thymidylate Synthase
Applications
Apoptosis
Smiles
NC1=NC (=O) C2=C ([NH]C=C2CCC3=CC=C (C=C3) C (=O) NC (CCC (O) =O) C (O) =O) N1
Molecular Formula
C20H21N5O6
Additionnal Information
Pemetrexed (LY231514) is a novel antifolate and antimetabolite for thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT) with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.
Storage Conditions
3 years -20°C powder

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