Products for Research Use Only
RegisterLogin

Belnacasan (VX-765)

CAT: 0957-S2228-200mgSize: 200 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0957-S2228-200mgSize:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
273404-37-8
Target
Caspase
Applications
Apoptosis
Smiles
CCOC1C (CC (=O) O1) NC (=O) C2CCCN2C (=O) C (C (C) (C) C) NC (=O) C3=CC (=C (C=C3) N) Cl
Molecular Formula
C24H33ClN4O6
Additionnal Information
Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM in a cell-free assay. Phase 2.
Storage Conditions
2 years -80 in solvent

Chemical Information

VX 765

Belnacasan is a dipeptide.

CAS Number273404-37-8
PubChem CID11398092
IUPAC Name(2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide
Molecular FormulaC24H33ClN4O6
Molecular Weight509.0
XLogP2.3
Topological Polar Surface Area140
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Heavy Atom Count35
Formal Charge0
Complexity818
SMILES
CCO[C@H]1[C@H](CC(=O)O1)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C(C)(C)C)NC(=O)C3=CC(=C(C=C3)N)Cl
InChI
InChI=1S/C24H33ClN4O6/c1-5-34-23-16(12-18(30)35-23)27-21(32)17-7-6-10-29(17)22(33)19(24(2,3)4)28-20(31)13-8-9-15(26)14(25)11-13/h8-9,11,16-17,19,23H,5-7,10,12,26H2,1-4H3,(H,27,32)(H,28,31)/t16-,17-,19+,23+/m0/s1
InChIKey
SJDDOCKBXFJEJB-MOKWFATOSA-N
Chemical Structure
2D Structure
2D structure of VX 765
CAS: 273404-37-8
CID: 11398092
Formula: C24H33ClN4O6
MW: 509.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight509.0
XLogP32.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Exact Mass508.2088625
Monoisotopic Mass508.2088625
Topological Polar Surface Area140 Ų
Heavy Atom Count35
Formal Charge0
Complexity818
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
E8329-01VQW-765
E8329-5mgVQW-765
E8329-100mgVQW-765
E8329-25mgVQW-765
E8329-1gVQW-765
S8593-01VX-984
S1335-01VX-150
S1335-5mgVX-150
S6005-25mgVX-702
S8593-100mgVX-984

Alternative Products

CatalogName
MBS386389-01VX-765 (Belnacasan)
C08374-1gBelnacasan (VX-765)
A10984-200VX-765 (Belnacasan) 200mg
A10984-25VX-765 (Belnacasan) 25mg
A10984-2VX-765 (Belnacasan) 2mg
2781-25VX-765
7143/50VX 765

Popular Products