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Afatinib

CAT: 0957-S1011-200mgSize: 200 mgDry Ice: YesHazardous: No
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CAT#:0957-S1011-200mgSize:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
850140-72-6
Synonyms
BIBW2992
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CN (C) CC=CC (=O) NC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=C (C=C3) F) Cl) OC4CCOC4
Molecular Formula
C24H25ClFN5O3
Additionnal Information
Afatinib inhibits EGFR/ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy.
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
A4746-25Afatinib

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