Afatinib (BIBW2992)

• Description :

  Irreversible EGFR/HER2 inhibitor

• Product Name Alternative :

  (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide

• Field of Research :

  JAK STAT Signaling EGFR Tyrosine Kinase EGFR Tyrosine Kinase HER2

• Purity :

  0.9883

• Form :

  A solid

• Solubility :

  ≥24.3 mg/mL in DMSO; insoluble in H2O; ≥42.1 mg/mL in EtOH with ultrasonic

• Smiles :

  CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4

• Molecular Formula :

  C24H25ClFN5O3

• Molecular Weight :

  485.94

• Shipping Conditions :

  Blue ice

• Storage Conditions :

  Store at -20°C.

• CAS Number :

  439081-18-2